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Biomarkers allow the early diagnosis of possible impacts at low levels of biological organization, to try to avoid or mitigate possible damage at higher levels of organization, such as at the population level 24

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The question, then arose, whether this increase in intraislet H 2 S biosynthesis is part of a protective mechanism (whereby increased H 2 S levels counteract the increased oxidative/nitrosative stress conditions during the process of islet cell death), or, alternatively, is it part of the pathophysiology of the disease (suppressing insulin production and contributing to β-cell destruction)