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In addition, GHK-Cu complexes have been recognized as excellent cosmetically therapeutic agents that can prevent oxidative stress in human skin [20], promote skin wound healing in rats [52], and ameliorate lipopolysaccharide-induced acute lung injury in mice [2]
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In rodent brain-injury models, GHK-Cu has been linked to decreased neuronal apoptosis and reduced edema, with one proposed mechanism involving the miR-339-5p/VEGFA pathway, which is active in post-ischemic and hemorrhagic conditions
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