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Increased cholesterol concentration competes with the drug for bilayer space, resulting in a larger hydrodynamic diameter due to a more structured bilayer ( Cholesterol concentration was also positively correlated with encapsulation efficiency (EE%), due to its impact on enhancing the mechanical strength, cohesion, and permeability of lipid bilayers in niosomes
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We start by providing an overview of the different types of CFE systems and the different components required for activity (Section 2)
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