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The limitations of such studies warrant consideration including the following: 1) none of the eligible studies had data on kidney stone composition 2) methods for diagnosis of kidney stone disease and MASLD varied considerably 3) different co-variates for adjusting the data were utilized 4) severity of MASLD, including degree of hepatic fat deposition and fibrosis was not clearly defined in many of the studies Etiology of Kidney Stones in the context of MASLD Both kidney stone disease and MASLD are associated with multiple metabolic risk factors, including obesity, diabetes, dyslipidemia, and hypertension
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