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It’s well-tolerated by virtually all patients, with no significant side-effects reported in the research literature

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However, patients should reach out to their GoalBMI Wellness provider promptly if they experience: Severe nausea that does not improve with dietary adjustments after 2-3 weeks Vomiting that prevents normal eating and drinking for more than 24 hours Severe stomach pain, especially if it radiates to the back Signs of dehydration dizziness, dark urine, significantly reduced urination Swelling of the face, lips, tongue, or throat Difficulty breathing after injection Persistent constipation that does not respond to dietary changes Any new symptoms you are not sure about when in doubt, reach out Do not stop tirzepatide on your own without speaking with your provider first