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Hyperglycemia and dyslipidemia promote depressive symptoms by increasing systemic inflammation and reducing brain levels of serotonin (5-hydroxytryptamine, 5-HT) (Sarmiento-Ortega et al., 2025)
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Interestingly, GPx4 abundance is 75% heritable and exhibits at least four-fold variation between cohorts of donors, predisposing their RBC to increased susceptibility to haemolysis [166]
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