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Red flags in a CoA: No lot number or a lot number that doesn't match the vial HPLC purity below 98% with no explanation Missing mass spectrometry data Testing date that predates the listed synthesis date No information on the analytical method used "In-house testing" language with no third-party verification Third-Party Testing: The Gold Standard The most reliable QA approach for research peptides is third-party independent testing — where a laboratory other than the manufacturer performs the analytical verification