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The RDKit cheminformatics software is freely available under the BSD licence ( ALOGPS 2.1 used for reference value generation is freely available online ( References Huuskonen, J
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Although N-acetylcysteine (NAC) directly influences the pool of extracellular cystine and intracellular cysteine via a series of plasmatic redox reactions, in order to be effective, intracellular cysteine precursors must be designed to enter erythrocytes rapidly and use high activity enzymes within erythrocytes to liberate cysteine (Whillier et al., 2009
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