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That of course would have the advantage of very few injections,” Lebwohl noted

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Such neurotrophic/protective actions appear to translate across neuronal cell types as well neurodegenerative disorders, as GLP-1R agonists have now been reported as effective in cellular and animal models of AD, stroke, ALS and peripheral neuropathy [191, 196-202], spurring repositioning of exendin-4 in recently started clinical trials of AD, PD and peripheral neuropathy (ClinicalTrials.gov identifier: NCT01255163, NCT01174810 and NCT00855439, respectively)