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The restoration of mitochondrial function by pharmacological interventions, such as sacubitril/valsartan (Sac/Val), effectively suppressed STING pathway activation, suggesting that mitochondrial integrity is essential for limiting inflammatory cascades in DKD (340)
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New SC continue to increase, acting primarily by increasing synaptic levels of DA, 5-HT, and norepinephrine (NA) in the brain 45
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