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Applications of Metabolite Analysis in the Pentose Phosphate Pathway Metabolite analysis in the PPP provides crucial insights into the pathway's role in various physiological and pathological contexts
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In the classic two-stage mouse skin carcinogenesis model, by which tumors are initiated by DMBA and promoted by repeated dosing with 12- O -tetradecanoylphorbol 13-acetate (TPA), the results showed that sulforaphane inhibited incidence and multiplicity of tumors during the promotion stage instead of the initiation stage 66
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