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Oxidative Stress from Even-Electron Metal-Thiol Conjugates: A Case for Mercury Oxidative stress is loosely defined as a condition of impaired physiological balance between the energy-producing oxidative metabolism of nutritional carbon substrates, oxygen supply to the cells and the concentrations of antioxidant compounds, which is reflected at the biochemical level into an imbalance of the dynamic physiological ratio of “oxidizing” and of “reducing” processes and related molecules [11]