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Total RNA was extracted using TRIzol reagent (Sigma-Aldrich, T9424) following the manufacturer’s protocol

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Low expression of β-arrestin 1, but not β-arrestin 2, in GH- and PRL-secreting pituitary tumors correlates with a reduced recycling rate of SSTR2 and better SS analogs response in terms of GH suppression, both in vitro and in vivo (67)