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This is achieved through downregulation of β-catenin transcription factor-7-like-2 (TCF7L2) mRNA and suppression of downstream Wnt/β-catenin signaling target genes, including Cyclin D1, c-Myc, Snail, Vimentin, matrix metalloproteinase 2 (MMP2), and MMP9, in human CRC cells ( 3.2 Effect of the Wnt/β-catenin signaling pathway on angiogenesis in CRC Angiogenesis is a critical process in the progression of tumor growth and metastasis
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Oral BPC-157 primarily targets the digestive tract and systemic inflammation, whereas injectable versions are often used for localized musculoskeletal repair
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