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The rats received pentadecapeptide BPC 157 (0.16 μg/ml) in drinking water (12 ml/rat) until sacrifice or drinking water only
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In addition, our results indicate that there is an altered flux through the methylation cycle in COC users, which may be due to the increased demand for methyl-group donors that drive the COMT-mediated methylation of E2 and E1
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