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Thereby, the reported myotendinous junction recovery [43] and restoration of full function with the stable gastric pentadecapeptide BPC 157 therapy [43] might have particular therapy potential

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The short version is simple: semaglutide remains the most established GLP-1 baseline, tirzepatide is the strongest FDA-approved option, retatrutide currently sets the highest raw efficacy ceiling but is still investigational, and CagriSema is the only multi-peptide fat-loss combination with Phase 3 data