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PGC-1α, which does not bind directly to DNA, is recruited to chromatin and acts as a pleiotropic regulator by interacting with nuclear receptors or activating transcription factors, thus promoting mitochondrial biogenesis [28, 29]

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Supply Duration:1 month supply

Upper end: 1,000 mg daily is common in studies and generally well tolerated, but above that you are mostly paying for what your body cannot use