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Lark et al (48) found that including 2.5% tryptophan in the diet of DSS rats for five weeks prevented the development of hypertension
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Treatment of DCIS tissue with sulforaphane was shown to activate miR-140 expression and downregulation of SOX9 and ALDH1 (important in stem cell regulation, and targets of miR-140 in DCIS stem-like cells), resulting in a decrease in stem-like cell frequency in vitro and a significant inhibition of tumor growth in vivo
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