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Figure 3 5 Role of related signalling pathways in NDDs 5.1 NF-κB NF-κB, a family of transcription factors comprising p65, RelB, c-Rel, NF-κB1, and NF-κB2, serves as a central orchestrator of neuroinflammatory and OS pathways by governing the expression of pro-inflammatory cytokines and OS-associated enzymes (iNOS, COX-2) (Ghosh et al., 2012)

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